兔抗CHRNA3多克隆抗体

Background:

This locus encodes a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. This locus encodes an alpha-type subunit, as it contains characteristic adjacent cysteine residues. The encoded protein is a ligand-gated ion channel that likely plays a role in neurotransmission. Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer. Alternatively spliced transcript variants have been described.

Applications:

ELISA, WB, IHC

Name of antibody:

CHRNA3

Immunogen:

Synthetic peptide of human CHRNA3

Full name:

cholinergic receptor, nicotinic, alpha 3 (neuronal)

Synonyms：

LNCR2, PAOD2, NACHRA3

SwissProt:

P32297

ELISA Recommended dilution:

2000-10000

IHC positive control:

Human ovarian cancer

IHC Recommend dilution:

15-50

WB Predicted band size:

55 kDa

WB Positive control:

Hela cells

WB Recommended dilution:

1000-5000