兔抗CHRNA10多克隆抗体.pdf

Background:

Ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding may induce an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane. In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma.

Applications:

ELISA, IHC

Name of antibody:

CHRNA10

Immunogen:

Synthetic peptide of human CHRNA10

Full name:

cholinergic receptor, nicotinic, alpha 10 (neuronal)

Synonyms：

no

SwissProt:

Q9GZZ6

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human colon cancer and Human lung cancer

IHC Recommend dilution:

25-100