兔抗NBN多克隆抗体

Background:

Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation.

Applications:

ELISA, IHC

Name of antibody:

NBN

Immunogen:

Synthetic peptide of human NBN

Full name:

nibrin

Synonyms：

ATV, NBS, P95, NBS1, AT-V1, AT-V2

SwissProt:

O60934

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human breast cancer and Human lung cancer

IHC Recommend dilution:

25-100