兔抗OPRM1(Phospho-Ser375)多克隆抗体

Background:

This gene encodes one of at least three opioid receptors in humans; the mu opioid receptor (MOR). The MOR is the principal target of endogenous opioid peptides and opioid analgesic agents such as beta-endorphin and enkephalins. The MOR also has an important role in dependence to other drugs of abuse, such as nicotine, cocaine, and alcohol via its modulation of the dopamine system. The NM_001008503.2:c.118A>G allele has been associated with opioid and alcohol addiction and variations in pain sensitivity but evidence for it having a causal role is conflicting.

Applications:

WB

Name of antibody:

OPRM1(Phospho-Ser375)

Immunogen:

Peptide sequence around phosphorylation site of serine 375(H-P-S(p)-T-A) derived from Human Opioid Receptor.

Full name:

opioid receptor, mu 1

Synonyms：

MOP; MOR; LMOR; MOR1; OPRM; M-OR-1

SwissProt:

P35372

WB Predicted band size:

45 kDa

WB Positive control:

Rat brain and mouse brain tissue lysates

WB Recommended dilution:

500-1000