中文名称: 兔抗TXNIP多克隆抗体
英文名称:Anti-TXNIP rabbit polyclonal antibody
别 名: THIF; VDUP1; HHCPA78; EST01027
相关类别:一抗
储 存: 冷冻(-20℃)
宿 主: Rabbit
抗 原: TXNIP
反应种属: Human, Mouse, Rat
标 记 物:Unconjugate
克隆类型:rabbit polyclonal
技术规格
Background: | May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells. Acts as a suppressor of tumor cell growth. Inhibits the proteasomal degradation of DDIT4, and thereby contributes to the inhibition of the mammalian target of rapamycin complex 1 (mTORC1). |
Applications: | ELISA, IHC |
Name of antibody: | TXNIP |
Immunogen: | Synthetic peptide of humanTXNIP |
Full name: | thioredoxin interacting protein |
Synonyms: | THIF; VDUP1; HHCPA78; EST01027 |
SwissProt: | Q9H3M7 |
ELISA Recommended dilution: | 2000-10000 |
IHC positive control: | Human esophagus cancer |
IHC Recommend dilution: | 30-150 |