兔抗MTOR(Phospho-Ser2448)多克隆抗体

Background:

The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene.

Applications:

WB, IHC, IF

Name of antibody:

MTOR(Phospho-Ser2448)

Immunogen:

Synthetic peptide of human MTOR

Full name:

mechanistic target of rapamycin kinase

Synonyms:

SKS; FRAP; FRAP1; FRAP2; RAFT1; RAPT1

SwissProt:

P42345

IHC positive control:

Human breast carcinoma

IHC Recommend dilution:

50-100

WB Predicted band size:

289 kDa

WB Positive control:

293 cells treated with PMA

WB Recommended dilution:

500-1000

IF positive control:

MCF cells

IF Recommend dilution:

100-200