中文名称:兔抗CCM2多克隆抗体
英文名称:Anti-CCM2 rabbit polyclonal antibody
别 名: CCM2 scaffolding protein; OSM; C7orf22; PP10187
相关类别:一抗
储 存: 冷冻(-20℃)
宿 主: Rabbit
抗 原: CCM2
反应种属:Human
标记物: Unconjugate
克隆类型:rabbit polyclonal
技术规格
Background: | This gene encodes a scaffold protein that functions in the stress-activated p38 Mitogen-activated protein kinase (MAPK) signaling cascade. The protein interacts with SMAD specific E3 ubiquitin protein ligase 1 (also known as SMURF1) via a phosphotyrosine binding domain to promote RhoA degradation. The protein is required for normal cytoskeletal structure, cell-cell interactions, and lumen formation in endothelial cells. Mutations in this gene result in cerebral cavernous malformations. Multiple transcript variants encoding different isoforms have been found for this gene. |
Applications: | ELISA, IHC |
Name of antibody: | CCM2 |
Immunogen: | Fusion protein of human CCM2 |
Full name: | CCM2 scaffolding protein |
Synonyms: | OSM; C7orf22; PP10187 |
SwissProt: | Q9BSQ5 |
ELISA Recommended dilution: | 2000-5000 |
IHC positive control: | Human esophagus cancer |
IHC Recommend dilution: | 20-100 |