兔抗IFNB1多克隆抗体

Background:

This gene encodes a cytokine that belongs to the interferon family of signaling proteins, which are released as part of the innate immune response to pathogens. The protein encoded by this gene belongs to the type I class of interferons, which are important for defense against viral infections. In addition, type I interferons are involved in cell differentiation and anti-tumor defenses. Following secretion in response to a pathogen, type I interferons bind a homologous receptor complex and induce transcription of genes such as those encoding inflammatory cytokines and chemokines. Overactivation of type I interferon secretion is linked to autoimmune diseases. Mice deficient for this gene display several phenotypes including defects in B cell maturation and increased susceptibility to viral infection.

Applications:

ELISA, IHC

Name of antibody:

IFNB1

Immunogen:

Synthetic peptide of human IFNB1

Full name:

interferon, beta 1, fibroblast

Synonyms:

IFB; IFF; IFNB; IFN-beta

SwissProt:

P01574

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human esophagus cancer and human thyroid cancer

IHC Recommend dilution:

30-150