兔抗VDR(Phospho-Ser208)多克隆抗体

Background:

This gene encodes the nuclear hormone receptor for vitamin D3. This receptor also functions as a receptor for the secondary bile acid lithocholic acid. The receptor belongs to the family of trans-acting transcriptional regulatory factors and shows sequence similarity to the steroid and thyroid hormone receptors. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways, such as those involved in the immune response and cancer.

Applications:

WB

Name of antibody:

VDR(Phospho-Ser208)

Immunogen:

Peptide sequence around phosphorylation site of serine 208 (A-L-S(p)-P-V) derived from Human Vitamin D Receptor.

Full name:

vitamin D (1,25- dihydroxyvitamin D3) receptor

Synonyms：

NR1I1; PPP1R163

SwissProt:

P11473

WB Predicted band size:

48 kDa

WB Positive control:

HT29 cells lysates treated with Heatshock

WB Recommended dilution:

500-1000