兔抗MET(Ab-1003)多克隆抗体

Background:

The proto-oncogene MET product is the hepatocyte growth factor receptor and encodes tyrosine-kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. Various mutations in the MET gene are associated with papillary renal carcinoma. Two transcript variants encoding different isoforms have been found for this gene.

Applications:

WB, IHC, IF

Name of antibody:

MET(Ab-1003)

Immunogen:

Synthesized non-phosphopeptide derived from human c-Met around the phosphorylation site of tyrosine 1003 (V-D-Y(p)-R-A).

Full name:

MET proto-oncogene, receptor tyrosine kinase

Synonyms：

HGFR; AUTS9; RCCP2; c-Met

SwissProt:

P08581

IHC positive control:

Human brain tissue

IHC Recommend dilution:

50-100

WB Predicted band size:

156 kDa

WB Positive control:

HepG2 cells lysate

WB Recommended dilution:

500-3000

IF positive control:

A549 cells

IF Recommend dilution:

100-500